Wine, Applied Immunology

Research output

Publications

  1. Gut microbiome-derived indoles differentially suppress type III secretion system-associated virulence in Escherichia coli and Salmonella enterica

    M. Shvarthburg et al.Frontiers in Microbiology 17, 19026382026

  2. Artificial light at night disrupts immune rhythms in wild rodents under semi-natural conditions

    H. Vardi-Naim et al.Environmental Pollution, 1277742026

  3. Dual-mode electrochemical point-of-care detection, quantification and profiling of pathogens

    N. Sal-Man et al.US Patent App. 18/866,6582025Patent

  4. Monoclonal antibody-based biosensor for point-of-care detection of type iii secretion system expressing pathogens

    Y. Wine et al.US Patent App. 18/254,4892025Patent

  5. A dual-channel electrochemical biosensor enables concurrent detection of pathogens and antibiotic resistance

    D. Gunasekaran et al.Biosensors and Bioelectronics 257, 1163142024

  6. Monoclonal antibody and uses thereof for the treatment and diagnosis of multidrug-resistant pathogenic bacterial infections

    Y. Wine et al.US Patent App. 17/996,0132024Patent

  7. Erratum to “Maternal Immunization During the Second Trimester with BNT162b2 mRNA Vaccine Induces a Robust IgA Response in Human Milk: A Prospective Cohort Study”

    A. Kigel et al.The American Journal of Clinical Nutrition 118 (5), 10682023Erratum

  8. Antibody isolation from human synthetic libraries of single-chain antibodies and analysis using NGS

    A. Amir et al.Phage Display: Methods and Protocols, 347-3722023Chapter

  9. Maternal immunization during the second trimester with BNT162b2 mRNA vaccine induces a robust IgA response in human milk: a prospective cohort study

    A. Kigel et al.The American Journal of Clinical Nutrition 118 (3), 572-5782023

  10. Longitudinal kinetics of RBD+ antibodies in COVID-19 recovered patients over 14 months

    T. Eyran et al.PLoS Pathogens 18 (6), e10105692022

  11. BNT162b2 mRNA vaccine elicited antibody response in blood and milk of breastfeeding women

    M. Rosenberg-Friedman et al.Nature Communications 12 (1), 62222021

  12. The longitudinal kinetics of antibodies in COVID-19 recovered patients over 14 months

    T. Eyran et al.MedRxiv, 2021.09.16.212636932021Preprint

  13. When a virus lies in wait

    D. Taussig et al.Elife 10, e711212021

  14. Antibody repertoire analysis of tumor-infiltrating B cells reveals distinct signatures and distributions across tissues

    L. Aizik et al.Frontiers in immunology 12, 7053812021

  15. BNT162b2 COVID-19 mRNA vaccine elicits a rapid and synchronized antibody response in blood and milk of breastfeeding women

    M.R. Friedman et al.MedRxiv, 2021.03.06.212526032021Preprint

  16. Rapid seroconversion and persistent functional IgG antibodies in severe COVID-19 patients correlates with an IL-12p70 and IL-33 signature

    A. Munitz et al.Scientific Reports 11 (1), 34612021

  17. PASA: Proteomic analysis of serum antibodies web server

    O. Avram et al.PLoS computational biology 17 (1), e10086072021

  18. Monoclonal antibody-based biosensor for point-of-care detection of type III secretion system expressing pathogens

    Y. Hillman et al.Analytical chemistry 93 (2), 928-9352021

  19. The Frequency of SARS-CoV-2 Specific Memory B Cells in COVID-19 Recovered Patients Remain Stable While Antibodies Decay Over Time

    A. Vaisman-Mentesh et al.Available at SSRN 37517882020Preprint

  20. Engineered B cells expressing an anti-HIV antibody enable memory retention, isotype switching and clonal expansion

    A.D. Nahmad et al.Nature communications 11 (1), 58512020

  21. SARS-CoV-2 specific memory B cells frequency in recovered patient remains stable while antibodies decay over time

    A. Vaisman-Mentesh et al.MedRxiv, 2020.08.23.201797962020Preprint

  22. The molecular mechanisms that underlie the immune biology of anti-drug antibody formation following treatment with monoclonal antibodies

    A. Vaisman-Mentesh et al.Frontiers in immunology 11, 19512020

  23. SARS-CoV-2 serological testing using electrochemiluminescence reveals a rapid onset of seroconversion in severe COVID-19 patients

    A. Munitz et al.medRxiv, 2020.06.28.201418382020Preprint

  24. Production of F(ab′)2 from Monoclonal and Polyclonal Antibodies

    S. Rosenstein et al.Current Protocols in Molecular Biology 131 (1), e1192020Chapter

  25. Engineered B Cells Undergo Antigen Induced Activation to Allow Memory Retention, Class Switch Recombination and Clonal Selection in Mice

    A.D. Nahmad et al.Molecular Therapy 28 (4), 63-632020Abstract

  26. B cells engineered to express an anti-HIV antibody allow memory retention, class switch recombination and clonal selection in mice

    A.D. Nahmad et al.bioRxiv, 2020.02.28.9708222020Preprint

  27. An anti-bacterial monoclonal antibody that targets pathogenic bacteria expressing the type 3 secretion system for therapeutic and diagnostic applications

    Y. Hillman et al.Authorea 2020 (0111)2020Preprint

  28. Molecular landscape of anti-drug antibodies reveals the mechanism of the immune response following treatment with TNFα antagonists

    A. Vaisman-Mentesh et al.Frontiers in immunology 10, 29212019

  29. ENGINEERING B CELLS FOR A REGULATED, IMMUNODOMINANT AND EVOLVING TREATMENT FOR HIV INFECTIONS

    A. Nahmad et al.Human Gene Therapy 30 (12), A12-A132019Abstract

  30. A NOVEL SUBSET OF CD4+ T CELL EXPRESSING THE HIGH AFFINITY Fc gamma RECEPTOR LINKS ANTIBODY AND T CELL IMMUNITY

    D. Rasoulouniriana et al.Human Gene Therapy 30 (12), A17-A172019Abstract

  31. A distinct subset of FcγRI-expressing Th1 cells exert antibody-mediated cytotoxic activity

    D. Rasoulouniriana et al.The Journal of clinical investigation 129 (10), 4151-41642019

  32. Antibody-based nanotechnology

    Y. Hillman et al.Nanotechnology 30 (28), 2820012019

  33. Proteomic identification of antibodies

    G.M. Georgiou et al.United States Patent and Trademark Office2019Patent

  34. Proteomic identification of antibodies

    J. Lavinder et al.US Patent 10,175,2492019Patent

  35. ASAP, A Webserver for Immunoglobulin-Sequencing Analysis Pipeline

    O. Avram et al.Frontiers in Immunology 9, 16862018

  36. Monitoring phage biopanning by next-generation sequencing

    A. Vaisman-Mentesh et al.Phage Display: Methods and Protocols, 463-4732017Chapter

  37. Reproducibility and reuse of adaptive immune receptor repertoire data

    F. Breden et al.Frontiers in immunology 8, 14182017

  38. Proteomic identification of antibodies

    J. Lavinder et al.US Patent 9,146,2412015Patent

  39. Serology in the 21st century: the molecular-level analysis of the serum antibody repertoire

    Y. Wine et al.Current opinion in immunology 35, 89-972015

  40. Protein products obtained by site‐preferred partial crosslinking in protein crystals and “liberated” by redissolution

    M. Buch et al.Biotechnology and Bioengineering 111 (7), 1296-13032014

  41. Systematic characterization and comparative analysis of the rabbit immunoglobulin repertoire

    J.J. Lavinder et al.PloS one 9 (6), e1013222014

  42. Proteomic identification of monoclonal antibodies from serum

    D.R. Boutz et al.Analytical chemistry 86 (10), 47582014

  43. Identification and characterization of the constituent human serum antibodies elicited by vaccination

    J.J. Lavinder et al.Proceedings of the National Academy of Sciences 111 (6), 2259-22642014

  44. Selective 351 nm photodissociation of cysteine-containing peptides for discrimination of antigen-binding regions of IgG fragments in bottom-up liquid chromatography–tandem mass spectrometry

    V.C. Cotham et al.Analytical chemistry 85 (11), 5577-55852013

  45. Molecular deconvolution of the monoclonal antibodies that comprise the polyclonal serum response

    Y. Wine et al.Proceedings of the National Academy of Sciences 110 (8), 2993-29982013

  46. High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire

    B.J. DeKosky et al.Nature biotechnology 31 (2), 166-1692013

  47. Antibody isolation from immunized animals: comparison of phage display and antibody discovery via V gene repertoire mining

    I. Saggy et al.Protein engineering, design & selection 25 (10), 539-5492012

  48. Re‐structuring protein crystals porosity for biotemplating by chemical modification of lysine residues

    N. Cohen‐Hadar et al.Biotechnology and bioengineering 108 (1), 1-112011

  49. Adjustment of protein crystal porosity for biotemplating: Chemical and protein engineering tools

    Y. Wine et al.AIP Conference Proceedings 1254 (1), 198-2032010Proceedings

  50. Modification of protein crystal packing by systematic mutations of surface residues: implications on biotemplating and crystal porosity

    Y. Wine et al.Biotechnology and bioengineering 104 (3), 444-4572009

  51. Protein crystal-mediated biotemplating

    N. Cohen-Hadar et al.Journal of Porous Media 12 (3)2009

  52. Protein Engineering and Chemical Crosslinking for Protein Crystal Mediated Biotemplating

    Y. WineTel-Aviv University2008Thesis

  53. Elucidation of the mechanism and end products of glutaraldehyde crosslinking reaction by X‐ray structure analysis

    Y. Wine et al.Biotechnology and bioengineering 98 (3), 711-7182007

  54. Protein-mediated nanoscale biotemplating

    S. Lagziel-Simis et al.Current opinion in biotechnology 17 (6), 569-5732006

  55. Monitoring the stability of crosslinked protein crystals biotemplates: A feasibility study

    N. Cohen‐Hadar et al.Biotechnology and bioengineering 94 (5), 1005-10112006